Job Description

Job Summary

IFF Health and Biosciences is looking for a Senior Scientist in our Microbiome & Microbiology R&D group. Our IFF laboratories are located within the Experimental Station research site in Wilmington, Delaware. The successful candidate will work with a highly interactive multidisciplinary research team applying rigorous, state of the art science toward the development and discovery of new health products.

We are searching for a candidate to join our immune health team who has broad experience working in BSL-2 laboratories and demonstrates conceptual and technical expertise that can be applied to investigations at the intersection of the Mucosal Microbiota and host immune systems.

Responsibilities

The primary responsibilities of the position will involve technical operations within our tissue culture facility establishing cellular assays using cell lines and primary cells isolated from humans and animals to study host microbiota interaction. In addition to cell culture responsibilities, familiarity with immunological techniques and technologies involved in downstream analysis and the ability to design and develop assays will be required. Most importantly the candidate will need to be team oriented, adaptable, self-motivated, and able to operate within a dynamic professional environment.

Desired Skills

• General lab organization, project planning, and task coordination among team members.
• Experience with pre-clinical models of host-microbe interaction.
• Sterile technique and safe handling of samples of human origin.
• Isolation of Peripheral Blood Mononuclear Cells (PBMCs) from human blood of healthy donors (Buffy coats/leukapheresis paks)
• Immunoaffinity separations of cells from PBMC preps. (ex: MACS / FACS).
• Primary immune cell isolation from host tissue and culture techniques.
• Cell line development by using CRISPR/Cas9.
• Tissue models; 3D (e.g.Mattek), organoids, co-cultures.
• Microscopy / immunohistology.
• Flow cytometry, cytometric bead arrays, Western Blot, ELISA, EliSpot, RNA-Seq.

Qualifications

• PhD in Immunology/Cell biology/mucosal Microbiology or related field.
• 6+ years of post-PhD laboratory research experience in immunology, cell biology, host-microbe interaction, microbiome-host relationships.
• 3+ years industrial experience is strongly preferred.
• Demonstrated knowledge of basic Immunology, cell biology, molecular biology, biochemistry techniques and microbiology,
• Sterile techniques and experience in the isolation and cultivation of microorganisms, preferably with experience in an anaerobic environment
• The successful candidate must be motivated, creative, have strong problem solving and critical thinking skills to meet technical objectives and milestones.
• Excellent written and verbal communication skills and the desire to work as a bench-scientist within a multidisciplinary team are required.

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